1/358 0.15-1.41 <font color=red>n</font> 从某种程度上来说呢，09-04 13:49:28-09-04 13:49:29<font color=blue>From a certain point of view,</font><br>2/358 1.65-4.35 <font color=red>hp</font> 睡觉可能是我们一天当中最脆弱的时刻了。09-04 13:49:28-09-04 13:49:32<font color=blue>Sleeping is one of the most vulnerable times in our day.</font><br>3/358 4.71-5.37 <font color=red>n</font> 白天的时候啊，09-04 13:49:29-09-04 13:49:30<font color=blue>During the day,</font><br>4/358 5.43-6.03 <font color=red>jd</font> 身体出了问题，09-04 13:49:30-09-04 13:49:30<font color=blue>Body problems,</font><br>5/358 6.15-7.95 <font color=red>n</font> 我们能够察觉到也能主动的调整。09-04 13:49:30-09-04 13:49:32<font color=blue>We can perceive and actively adjust.</font><br>6/358 8.25-9.69 <font color=red>aaa</font> 但在睡着的这段时间里，09-04 13:49:31-09-04 13:49:32<font color=blue>During this sleeping time,</font><br>7/358 9.87-10.95 <font color=red>n</font> 我们不能检查心率，09-04 13:49:32-09-04 13:49:33<font color=blue>We cannot check heart rate.</font><br>8/358 11.13-13.53 <font color=red>de</font> 更不知道自己的血氧在上升还是在下降，09-04 13:49:32-09-04 13:50:11<font color=blue>I don't even know if my blood oxygen is rising or falling.</font><br>9/358 13.77-16.59 <font color=red>jd</font> 甚至连呼吸这件平时根本不用操心的事儿。09-04 13:49:33-09-04 13:49:36<font color=blue>Even something as simple as breathing, which we normally don't have to worry about.</font><br>10/358 16.77-17.43 <font color=red>n</font> 一旦出了问题，09-04 13:49:34-09-04 13:49:35<font color=blue>Once there is a problem,</font><br>11/358 17.67-19.53 <font color=red>aaa</font> 就只能等大脑被动的发现异常，09-04 13:49:35-09-04 13:49:37<font color=blue>Then, it can only wait for the brain to passively discover abnormalities.</font><br>12/358 19.71-21.03 <font color=red>hp</font> 再把自己强行叫醒。09-04 13:49:35-09-04 13:49:38<font color=blue>Force yourself to wake up again.</font><br>13/358 21.33-22.47 <font color=red>n</font> 平时我们说一个人打鼾，09-04 13:49:36-09-04 13:49:38<font color=blue>Normally, when we say someone is snoring,</font><br>14/358 22.65-23.55 <font color=red>n</font> 听起来大概是这样的。09-04 13:49:37-09-04 13:49:39<font color=blue>Here's the gist of it.</font><br>15/358 25.35-26.85 <font color=red>jd</font> 而有些人的夜晚是这样的，09-04 13:49:37-09-04 13:49:39<font color=blue>And some people's nights are like this.</font><br>16/358 27.39-28.89 <font color=red>aaa</font> 其实是持续不断的鼾声。09-04 13:49:38-09-04 13:49:40<font color=blue>It's actually a continuous snoring sound.</font><br>17/358 29.19-30.4 <font color=red>bg</font> 接着突然消失。09-04 13:49:39-09-04 13:49:59<font color=blue>Then suddenly disappeared.</font><br>18/358 30.76-31.72 <font color=red>xss</font> 安静十几秒以后，09-04 13:49:39-09-04 13:51:06<font color=blue>After a few seconds of silence,</font><br>19/358 31.96-33.4 <font color=red>n</font> 伴随着一支猛烈的喘气，09-04 13:49:40-09-04 13:49:41<font color=blue>Accompanied by a powerful gasp,</font><br>20/358 33.76-34.84 <font color=red>hp</font> 呼吸再重新开始。09-04 13:49:41-09-04 13:49:43<font color=blue>Restart your breath.</font><br>21/358 35.32-36.58 <font color=red>n</font> 当他本人第二天醒来，09-04 13:49:41-09-04 13:49:43<font color=blue>When he woke up the next day,</font><br>22/358 36.76-38.26 <font color=red>jd</font> 可能完全不记得这一切。09-04 13:49:42-09-04 13:49:44<font color=blue>Perhaps I have completely forgotten all of this.</font><br>23/358 38.56-40.96 <font color=red>aaa</font> 只觉得头疼口干或者怎么睡的睡不够。09-04 13:49:43-09-04 13:49:46<font color=blue>I just feel like I have a headache, my mouth is dry, or that I didn't sleep enough.</font><br>24/358 41.26-41.74 <font color=red>n</font> 换句话说，09-04 13:49:43-09-04 13:49:44<font color=blue>In other words,</font><br>25/358 42.04-45.4 <font color=red>n</font> 睡觉是我们每天都要经历一次的控制权移交，09-04 13:49:44-09-04 13:49:46<font color=blue>Sleeping is a daily process of relinquishing control,</font><br>26/358 45.76-46.48 <font color=red>hp</font> 在睡着以后，09-04 13:49:45-09-04 13:49:47<font color=blue>After falling asleep,</font><br>27/358 46.66-48.94 <font color=red>jd</font> 我们只能依靠身体的自动调节机制。09-04 13:49:46-09-04 13:49:48<font color=blue>We can only rely on the body's self-regulating mechanisms.</font><br>28/358 49.36-50.02 <font color=red>n</font> 那么问题来了，09-04 13:49:46-09-04 13:49:47<font color=blue>So the question is,</font><br>29/358 50.32-52.06 <font color=red>aaa</font> 这套机制为什么会出错呢？09-04 13:49:47-09-04 13:49:48<font color=blue>What's wrong with this mechanism?</font><br>30/358 52.54-54.82 <font color=red>n</font> 当然无法在睡梦中主动解决问题时，09-04 13:49:48-09-04 13:49:50<font color=blue>Of course, it's impossible to actively solve problems while sleeping.</font><br>31/358 55.24-57.16 <font color=red>hp</font> 又该有什么提到自我判断呢？09-04 13:49:48-09-04 13:49:52<font color=blue>What else could be mentioned about self-judgment?</font><br>32/358 57.4-57.64 <font color=red>n</font> 大家好，09-04 13:49:49-09-04 13:49:50<font color=blue>Hello everyone,</font><br>33/358 57.76-59.32 <font color=red>jd</font> 我是攒前买咖啡续命的萨命菌。09-04 13:49:50-09-04 13:49:51<font color=blue>I'm a caffeine-fueled survivor.</font><br>34/358 59.5-62.66 <font color=red>aaa</font> 今天我们家来聊聊人类每天都要使用的系统睡眠。09-04 13:49:50-09-04 13:49:53<font color=blue>Today, we're going to talk about a system that humans use every day: sleep.</font><br>35/358 64.52-66.98 <font color=red>n</font> 人类呢每天大概要花三分之一的时间睡觉，09-04 13:49:51-09-04 13:49:54<font color=blue>Humans spend about one-third of their day sleeping.</font><br>36/358 67.31-73.1 <font color=red>n</font> 但这不只是因为身体需要体抗一些一些加小反睡眠期间身体忙得很，09-04 13:49:52-09-04 13:49:57<font color=blue>This is not only because the body needs to resist some of the negative effects of sleep deprivation, but also because...</font><br>37/358 73.65-75.449 <font color=red>jd</font> 大脑要处理白天积累的信息，09-04 13:49:52-09-04 13:49:55<font color=blue>The brain needs to process the information accumulated during the day.</font><br>38/358 75.75-76.59 <font color=red>hp</font> 巩固部分记忆，09-04 13:49:53-09-04 13:49:55<font color=blue>Reinforce some memories,</font><br>39/358 76.71-79.17 <font color=red>aaa</font> 并完成一系列神经系统维护有关的工作。09-04 13:49:54-09-04 13:49:56<font color=blue>And complete a series of tasks related to maintaining the nervous system.</font><br>40/358 79.64-82.4 <font color=red>n</font> 白天大脑会不断产生和释放各种物质，09-04 13:49:55-09-04 13:49:58<font color=blue>During the day, the brain constantly produces and releases various substances.</font><br>41/358 82.78-83.56 <font color=red>jd</font> 包括贝塔、09-04 13:49:55-09-04 13:49:56<font color=blue>including Beta,</font><br>42/358 83.68-83.86 <font color=red>hp</font> 淀粉、09-04 13:49:56-09-04 13:49:58<font color=blue>Starch,</font><br>43/358 83.98-85.3 <font color=red>aaa</font> 药蛋白和陶蛋白等等。09-04 13:49:57-09-04 13:49:58<font color=blue>Proteins and peptides, etc.</font><br>44/358 85.63-86.95 <font color=red>jd</font> 它的本身呢未必有害，09-04 13:49:57-09-04 13:49:59<font color=blue>Itself may not be harmful.</font><br>45/358 87.07-89.11 <font color=red>de</font> 但异常积累可能损害神经系统，09-04 13:49:58-09-04 13:50:21<font color=blue>However, abnormal accumulation can damage the nervous system.</font><br>46/358 89.41-92.62 <font color=red>n</font> 而睡眠可能正是大脑处理这些物质的重要时段。09-04 13:49:59-09-04 13:50:02<font color=blue>And sleep may be the important time for the brain to process these substances.</font><br>47/358 93.07-93.43 <font color=red>n</font> 与此同时，09-04 13:50:00-09-04 13:50:01<font color=blue>At the same time,</font><br>48/358 93.73-96.73 <font color=red>hp</font> 免疫代谢和激素系统也会随昼夜节率变化。09-04 13:50:00-09-04 13:50:05<font color=blue>The immune, metabolic and endocrine systems also change with the circadian rhythm.</font><br>49/358 97.0-100.42 <font color=red>aaa</font> 而睡眠正是这些机制正常运作的重要前提，09-04 13:50:01-09-04 13:50:03<font color=blue>And sleep is an essential prerequisite for the normal functioning of these mechanisms.</font><br>50/358 101.18-101.78 <font color=red>jd</font> 但问题在于，09-04 13:50:02-09-04 13:50:03<font color=blue>But the problem is that...</font><br>51/358 101.96-102.8 <font color=red>bg</font> 要启动这套系统，09-04 13:50:02-09-04 13:50:27<font color=blue>To start this system,</font><br>52/358 102.92-105.38 <font color=red>n</font> 身体就必须暂时关闭或者降低一部分能力。09-04 13:50:03-09-04 13:50:05<font color=blue>The body must temporarily shut down or reduce some of its functions.</font><br>53/358 105.78-105.9 <font color=red>n</font> 比如，09-04 13:50:04-09-04 13:50:05<font color=blue>For example,</font><br>54/358 106.14-107.46 <font color=red>jd</font> 对外的警觉和主动反应，09-04 13:50:04-09-04 13:50:06<font color=blue>Outward vigilance and proactive response,</font><br>55/358 107.94-109.38 <font color=red>aaa</font> 在快速演动睡眠期间，09-04 13:50:05-09-04 13:50:06<font color=blue>During rapid eye movement sleep,</font><br>56/358 109.56-111.0 <font color=red>hp</font> 体温调节能力会被削弱，09-04 13:50:06-09-04 13:50:09<font color=blue>The ability to regulate body temperature will be weakened.</font><br>57/358 111.18-112.44 <font color=red>n</font> 肌肉张力也会明显下降。09-04 13:50:06-09-04 13:50:08<font color=blue>Muscle tension will also decrease significantly.</font><br>58/358 112.86-115.14 <font color=red>n</font> 这些都是进入睡眠所付出的成本，09-04 13:50:07-09-04 13:50:09<font color=blue>These are the costs of falling asleep.</font><br>59/358 115.59-117.87 <font color=red>aaa</font> 一旦某个环节本来就存在薄弱之处，09-04 13:50:08-09-04 13:50:10<font color=blue>Once a particular link is already weak,</font><br>60/358 118.11-119.31 <font color=red>n</font> 成本就可能变成故障。09-04 13:50:09-09-04 13:50:10<font color=blue>Cost can become a failure.</font><br>61/358 119.65-119.83 <font color=red>jd</font> 于是，09-04 13:50:10-09-04 13:50:10<font color=blue>So,</font><br>62/358 120.13-122.95 <font color=red>n</font> 有人会在意识和身体不同步时遇到鬼压床，09-04 13:50:10-09-04 13:50:14<font color=blue>Some people experience sleep paralysis, a condition where they are conscious but unable to move.</font><br>63/358 123.46-126.28 <font color=red>hp</font> 也有人会在睡眠状态异常转换时梦游。09-04 13:50:11-09-04 13:50:15<font color=blue>Some people also experience sleepwalking during abnormal transitions in their sleeping state.</font><br>64/358 126.74-130.22 <font color=red>aaa</font> 还有一些人问题出现在一些看似最不可能出错的功能上。09-04 13:50:12-09-04 13:50:14<font color=blue>Some people have problems with features that seem the least likely to fail.</font><br>65/358 130.73-132.45 <font color=red>n</font> 呼吸说出来你可能不信，09-04 13:50:13-09-04 13:50:15<font color=blue>Breathing, if you say it out loud...</font><br>66/358 132.63-135.39 <font color=red>jd</font> 这其实是人类漫长进化过程中产生的 bug.09-04 13:50:13-09-04 13:50:16<font color=blue>This is actually a bug that has emerged in the long evolution of humans.</font><br>67/358 135.9-137.01 <font color=red>de</font> 为了直立行走和说话，09-04 13:50:14-09-04 13:50:48<font color=blue>In order to stand upright and speak,</font><br>68/358 137.25-138.27 <font color=red>n</font> 人人的脸变短了，09-04 13:50:15-09-04 13:50:16<font color=blue>Everyone's face is shorter.</font><br>69/358 138.6-140.04 <font color=red>aaa</font> 舌头相对于口腔变大了，09-04 13:50:15-09-04 13:50:17<font color=blue>The tongue is larger relative to the mouth.</font><br>70/358 140.28-141.42 <font color=red>n</font> 舌根下水道的咽雾，09-04 13:50:16-09-04 13:50:17<font color=blue>The throat, the sewer's breath.</font><br>71/358 141.66-142.98 <font color=red>hp</font> 喉头的位置也跟着下移。09-04 13:50:17-09-04 13:50:20<font color=blue>The position of the throat also shifted downwards.</font><br>72/358 143.3-145.309 <font color=red>jd</font> 这些变化让我们能够发出丰富的语音，09-04 13:50:17-09-04 13:50:19<font color=blue>These changes allow us to produce a wide range of voices.</font><br>73/358 145.66-147.49 <font color=red>n</font> 却也留下了一段又窄又软、09-04 13:50:18-09-04 13:50:20<font color=blue>However, it also left behind a narrow and soft passage.</font><br>74/358 147.73-149.17 <font color=red>aaa</font> 容易塌陷的口咽祈祷。09-04 13:50:19-09-04 13:50:20<font color=blue>Prayer for the collapse of the throat.</font><br>75/358 149.73-151.77 <font color=red>n</font> 白天有着扩烟肌蛋支撑问题还不大，09-04 13:50:19-09-04 13:50:23<font color=blue>The problem of supporting the egg with the enlarged diaphragm is not a big issue during the day.</font><br>76/358 151.89-153.39 <font color=red>jd</font> 但睡觉以后肌肉张力下降，09-04 13:55:21-09-04 13:55:23<font color=blue>But after sleeping, muscle tension decreases.</font><br>77/358 153.69-154.29 <font color=red>jd</font> 麻烦就来了。09-04 13:50:21-09-04 13:50:22<font color=blue>Trouble is coming.</font><br>78/358 154.79-156.23 <font color=red>hp</font> 如果你呢气道本身就比较窄，09-04 13:50:21-09-04 13:50:24<font color=blue>If your airways are already narrow,</font><br>79/358 156.41-157.73 <font color=red>aaa</font> 或者肌肉代偿能力比较弱，09-04 13:50:22-09-04 13:50:24<font color=blue>Or, the muscle compensation ability is weak.</font><br>80/358 158.1-160.5 <font color=red>n</font> 又或者大脑对于呼吸的调控不那么稳定，09-04 13:50:23-09-04 13:50:25<font color=blue>Or, the brain may not regulate breathing as stably.</font><br>81/358 160.92-164.37 <font color=red>de</font> 那么每次吸气都会让其道像一根吸管一样反复背下去。09-04 13:50:23-09-04 13:51:20<font color=blue>So, each inhalation will make the esophagus act like a straw and repeatedly go down.</font><br>82/358 164.72-166.31 <font color=red>jd</font> 有时候他会出现堵死的情况，09-04 13:50:24-09-04 13:50:25<font color=blue>Sometimes he gets stuck.</font><br>83/358 166.76-172.16 <font color=red>n</font> 这就是阻塞性睡眠呼吸暂停一次典型的 o s a 过程是怎么样的呢？09-04 13:50:25-09-04 13:50:27<font color=blue>Here's a typical OSA process, one time:</font><br>84/358 172.42-173.5 <font color=red>aaa</font> 先呢是气道变窄，09-04 13:50:25-09-04 13:50:27<font color=blue>First, the airway narrows.</font><br>85/358 173.86-175.9 <font color=red>hp</font> 软组织被气流吹得来回震动，09-04 13:50:26-09-04 13:50:30<font color=blue>The soft tissues were shaken back and forth by the airflow.</font><br>86/358 176.08-176.62 <font color=red>n</font> 产生鼾声，09-04 13:50:27-09-04 13:50:27<font color=blue>Snoring,</font><br>87/358 176.98-178.24 <font color=red>jd</font> 然后气到继续塌陷，09-04 13:50:27-09-04 13:50:29<font color=blue>Then, he was so angry that he continued to collapse.</font><br>88/358 178.6-179.38 <font color=red>aaa</font> 气流越来越小，09-04 13:50:28-09-04 13:50:29<font color=blue>The airflow is getting smaller.</font><br>89/358 179.94-180.84 <font color=red>n</font> 如果气流中断，09-04 13:50:29-09-04 13:50:30<font color=blue>If the airflow is interrupted,</font><br>90/358 181.02-182.28 <font color=red>n</font> 还可能进入呼吸暂停。09-04 13:50:30-09-04 13:50:32<font color=blue>There is also a risk of respiratory arrest.</font><br>91/358 182.58-183.36 <font color=red>aaa</font> 由于血氧不足，09-04 13:50:31-09-04 13:50:32<font color=blue>Due to low blood oxygen,</font><br>92/358 183.6-185.82 <font color=red>jd</font> 大脑会紧急触发一个微觉醒或者觉醒，09-04 13:50:32-09-04 13:50:34<font color=blue>The brain will trigger an emergency micro-awakening or awakening.</font><br>93/358 186.3-187.44 <font color=red>hp</font> 唤醒肌肉功能扩张，09-04 13:50:32-09-04 13:50:35<font color=blue>Activate muscle function and expand,</font><br>94/358 187.56-190.2 <font color=red>n</font> 气道患者此时突然会伴随一次明显的喘息，09-04 13:50:33-09-04 13:50:36<font color=blue>The patient suddenly experiences a noticeable wheezing in the airway.</font><br>95/358 190.38-191.52 <font color=red>n</font> 然后再次入睡。09-04 13:50:34-09-04 13:50:35<font color=blue>Then fall asleep again.</font><br>96/358 192.06-194.1 <font color=red>aaa</font> 整个过程一晚上可能循环几十上百次，09-04 13:50:34-09-04 13:50:38<font color=blue>The entire process may cycle dozens or hundreds of times in one night.</font><br>97/358 194.4-196.86 <font color=red>jd</font> 但这些微觉醒大多数时候患者是感觉不到的。09-04 13:50:35-09-04 13:50:38<font color=blue>However, most of these micro-awakens are not perceived by patients.</font><br>98/358 197.1-198.66 <font color=red>hp</font> 很多人看似睡了八六个小时，09-04 13:50:36-09-04 13:50:40<font color=blue>Many people seem to be sleeping for 6 hours and 30 minutes,</font><br>99/358 198.9-203.46 <font color=red>n</font> 但大脑整个晚上可能要经历几十甚至上百次故障重启的过程。09-04 13:50:37-09-04 13:50:42<font color=blue>However, the entire brain may experience dozens or even hundreds of failures and restarts throughout the night.</font><br>100/358 204.0-204.54 <font color=red>n</font> 长此以往，09-04 13:50:39-09-04 13:50:40<font color=blue>If this continues,</font><br>101/358 204.78-207.78 <font color=red>aaa</font> 身体被反复缺氧和睡眠碎片化来回折腾，09-04 13:50:39-09-04 13:50:41<font color=blue>Being repeatedly deprived of oxygen and sleep,</font><br>102/358 208.02-209.28 <font color=red>jd</font> 各种问题也是接踵而来。09-04 13:50:40-09-04 13:50:41<font color=blue>Various problems also came one after another.</font><br>103/358 209.89-210.49 <font color=red>n</font> 有研究显示，09-04 13:50:41-09-04 13:50:42<font color=blue>Studies have shown that</font><br>104/358 210.85-212.35 <font color=red>hp</font> o s a 和心血管疾病、09-04 13:50:41-09-04 13:50:44<font color=blue>o s a and cardiovascular disease,</font><br>105/358 212.59-212.77 <font color=red>aaa</font> 卒中、09-04 13:50:42-09-04 13:50:43<font color=blue>Death,</font><br>106/358 213.01-214.57 <font color=red>jd</font> 冠心病等风险显著相关，09-04 13:50:43-09-04 13:50:44<font color=blue>Significantly related to the risk of coronary heart disease,</font><br>107/358 214.93-215.53 <font color=red>n</font> 病情越严重，09-04 13:50:43-09-04 13:50:45<font color=blue>The more severe the condition,</font><br>108/358 215.71-216.19 <font color=red>n</font> 风险越高。09-04 13:50:44-09-04 13:50:45<font color=blue>Higher risk.</font><br>109/358 216.43-216.61 <font color=red>aaa</font> 另外，09-04 13:50:45-09-04 13:50:45<font color=blue>In addition,</font><br>110/358 216.91-219.43 <font color=red>hp</font> o s a 还和二型糖尿病密切相关，09-04 13:50:45-09-04 13:50:50<font color=blue>o s a is also closely related to type 2 diabetes,</font><br>111/358 219.79-221.83 <font color=red>jd</font> 反复缺氧和睡眠碎片化可能，09-04 13:50:46-09-04 13:50:47<font color=blue>Repeated hypoxia and fragmented sleep,</font><br>112/358 222.07-222.91 <font color=red>n</font> 扰乱血氧代谢，09-04 13:50:47-09-04 13:50:48<font color=blue>Disrupt blood oxygen metabolism,</font><br>113/358 223.21-224.47 <font color=red>n</font> 让病情更难控制。09-04 13:50:47-09-04 13:50:49<font color=blue>Make the condition more difficult to control.</font><br>114/358 225.01-225.55 <font color=red>aaa</font> 白天嗜睡、09-04 13:50:48-09-04 13:50:49<font color=blue>Daytime sleepiness</font><br>115/358 225.85-226.33 <font color=red>jd</font> 注意力下降、09-04 13:50:49-09-04 13:50:49<font color=blue>Attention decline,</font><br>116/358 226.57-227.53 <font color=red>n</font> 记忆力变差等问题，09-04 13:50:49-09-04 13:50:51<font color=blue>Memory problems, such as memory loss.</font><br>117/358 227.77-231.61 <font color=red>de</font> 同样和 o s a 相关并可能增加工伤和交通事故的风险。09-04 13:50:50-09-04 13:51:47<font color=blue>Also related to o s a and may increase the risk of work-related injuries and traffic accidents.</font><br>118/358 231.97-233.47 <font color=red>aaa</font> 这时候可能有差尔要说了，09-04 13:50:51-09-04 13:50:53<font color=blue>At this time, there might be a difference of opinion.</font><br>119/358 233.65-235.69 <font color=red>n</font> 这不是肥胖人群才会得的病吗？09-04 13:50:51-09-04 13:50:54<font color=blue>This isn't a disease that only obese people get, is it?</font><br>120/358 235.99-236.05 <font color=red>jd</font> 啊，09-04 13:50:52-09-04 13:50:53<font color=blue>Oh,</font><br>121/358 236.29-238.45 <font color=red>hp</font> 还真不是肥胖和颈围大，09-04 13:50:53-09-04 13:50:58<font color=blue>It's not just about being overweight and having a large neck circumference.</font><br>122/358 238.75-240.86 <font color=red>n</font> 确实是 o s a 的重要风险因素。09-04 13:50:53-09-04 13:50:55<font color=blue>Indeed, it is an important risk factor for OSA.</font><br>123/358 241.17-243.9 <font color=red>aaa</font> 但下颌后缩气道天生就比较窄的人，09-04 13:50:54-09-04 13:50:56<font color=blue>But for people with a naturally narrow airway due to the receding jaw,</font><br>124/358 244.02-244.92 <font color=red>jd</font> 同样会得 o s c.09-04 13:50:55-09-04 13:50:57<font color=blue>Also, you will get o.s.c.</font><br>125/358 245.34-246.84 <font color=red>n</font> 即使他们的 b m y 很正常，09-04 13:50:56-09-04 13:50:58<font color=blue>Even if their BMY is normal,</font><br>126/358 247.14-248.28 <font color=red>n</font> 中老年男性决定后，09-04 13:50:56-09-04 13:50:58<font color=blue>Middle-aged and elderly men decided to,</font><br>127/358 248.4-251.28 <font color=red>aaa</font> 女性有家族史的人也都属于高风险人群。09-04 13:50:57-09-04 13:51:00<font color=blue>Women with a family history of heart disease are also considered high-risk individuals.</font><br>128/358 251.68-253.0 <font color=red>jd</font> 而且 o s o 还有一个特点，09-04 13:50:58-09-04 13:51:00<font color=blue>In addition, o s o also has a characteristic,</font><br>129/358 253.32-254.34 <font color=red>hp</font> 诊断力很低。09-04 13:50:58-09-04 13:51:01<font color=blue>Low diagnostic ability.</font><br>130/358 254.93-255.41 <font color=red>n</font> 据估计呢，09-04 13:50:59-09-04 13:51:00<font color=blue>According to estimates,</font><br>131/358 255.53-260.26 <font color=red>n</font> 全球三十到六十九岁人群中有大概九点三六亿 o s a 患者，09-04 13:51:00-09-04 13:51:04<font color=blue>There are approximately 936 million people aged between 30 and 69 worldwide who have OSA.</font><br>132/358 260.63-263.51 <font color=red>aaa</font> 我国 o s a 总体患病率大概是百分之十一点八，09-04 13:51:01-09-04 13:51:03<font color=blue>The overall prevalence of OSA in China is approximately 11.8%.</font><br>133/358 263.99-266.33 <font color=red>jd</font> 但大量患者仍没有被发现和确诊。09-04 13:51:01-09-04 13:51:04<font color=blue>However, a large number of patients have not been discovered and diagnosed.</font><br>134/358 266.82-267.48 <font color=red>n</font> 为什么这么低呢？09-04 13:51:02-09-04 13:51:04<font color=blue>Why is it so low?</font><br>135/358 267.81-268.83 <font color=red>hp</font> 一个很现实的原因是，09-04 13:51:03-09-04 13:51:05<font color=blue>A very realistic reason is,</font><br>136/358 269.01-272.37 <font color=red>jd</font> 目前诊断 oa 的精标准是多导睡眠监测。09-04 13:56:04-09-04 13:56:06<font color=blue>Currently, the gold standard for diagnosing OA is polysomnography.</font><br>137/358 272.49-274.58 <font color=red>aaa</font> p sg 需要去专门的科室挂号，09-04 13:51:04-09-04 13:51:06<font color=blue>p sg needs to go to a specialized department for registration.</font><br>138/358 274.7-276.32 <font color=red>n</font> 贴满电机和传感器睡一整晚。09-04 13:51:05-09-04 13:51:06<font color=blue>Sleep with a bunch of motors and sensors.</font><br>139/358 276.63-278.13 <font color=red>jd</font> 根据报告制定相应的方案。09-04 13:51:05-09-04 13:51:07<font color=blue>Based on the report, develop the appropriate plan.</font><br>140/358 278.25-279.27 <font color=red>n</font> 很多人都觉得太麻烦，09-04 13:51:06-09-04 13:51:08<font color=blue>Many people think it's too complicated.</font><br>141/358 279.39-279.93 <font color=red>hp</font> 选择了放弃。09-04 13:51:07-09-04 13:51:09<font color=blue>I chose to give up.</font><br>142/358 280.53-283.77 <font color=red>aaa</font> 那有没有一些简单的方式可以帮我们进行初步筛查呢？09-04 13:51:07-09-04 13:51:09<font color=blue>Are there any simple ways to help us with preliminary screening?</font><br>143/358 284.12-284.15 <font color=red>xss</font> 啊，09-04 13:51:08-09-04 13:51:48<font color=blue>Oh,</font><br>144/358 284.27-284.75 <font color=red>n</font> 也是有的。09-04 13:51:09-09-04 13:51:10<font color=blue>Also, there are.</font><br>145/358 285.27-286.77 <font color=red>jd</font> 如果你长期严重打鼾，09-04 13:51:09-09-04 13:51:11<font color=blue>If you have chronic and severe snoring,</font><br>146/358 287.13-288.21 <font color=red>n</font> 晨起口干头疼，09-04 13:51:10-09-04 13:51:12<font color=blue>Waking up with a dry mouth and headache,</font><br>147/358 288.45-289.53 <font color=red>hp</font> 白天总是容易犯困，09-04 13:51:11-09-04 13:51:14<font color=blue>I often feel sleepy during the day.</font><br>148/358 289.94-291.77 <font color=red>aaa</font> 就应该进一步关注自己的睡眠健康了。09-04 13:51:11-09-04 13:51:13<font color=blue>You should pay more attention to your sleep health.</font><br>149/358 292.29-295.17 <font color=red>n</font> 现在一些可穿戴设备也能够监测到夜间，09-04 13:51:12-09-04 13:51:14<font color=blue>Currently, some wearable devices can also monitor at night.</font><br>150/358 295.35-296.13 <font color=red>jd</font> 心率异常升高、09-04 13:51:13-09-04 13:51:14<font color=blue>Abnormal heart rate increase,</font><br>151/358 296.43-297.75 <font color=red>n</font> 血氧频繁下降等信号，09-04 13:51:14-09-04 13:51:15<font color=blue>Frequent drops in blood oxygen levels,</font><br>152/358 298.15-299.59 <font color=red>bg</font> 虽然不能替代医疗及诊断，09-04 13:51:14-09-04 13:51:48<font color=blue>Although it cannot replace medical care and diagnosis,</font><br>153/358 299.71-301.63 <font color=red>aaa</font> 但可以帮你判断要不要进一步检查。09-04 13:51:15-09-04 13:51:17<font color=blue>But I can help you determine whether or not further examination is necessary.</font><br>154/358 301.87-302.17 <font color=red>hp</font> 说到底，09-04 13:51:16-09-04 13:51:17<font color=blue>Ultimately,</font><br>155/358 302.35-303.67 <font color=red>jd</font> o s a 之所以棘手，09-04 13:51:16-09-04 13:51:18<font color=blue>The reason why "o s a" is so tricky,</font><br>156/358 303.79-304.69 <font color=red>n</font> 并不是因为它伤害大，09-04 13:51:17-09-04 13:51:19<font color=blue>It's not because it hurts,</font><br>157/358 304.87-307.57 <font color=red>n</font> 而是因为它发生在你不能掌控自己身体的时候。09-04 13:51:18-09-04 13:51:20<font color=blue>Instead, it happens when you can't control your own body.</font><br>158/358 307.89-311.28 <font color=red>aaa</font> 这意味着很多人都需要一个能在睡眠过程中持续感知，09-04 13:51:18-09-04 13:51:21<font color=blue>This means that many people need a device that can continuously monitor their condition during sleep.</font><br>159/358 311.52-313.62 <font color=red>jd</font> 实是判断动态响应的可靠系统。09-04 13:51:20-09-04 13:51:21<font color=blue>This is a reliable system for evaluating dynamic responses.</font><br>160/358 313.86-314.4 <font color=red>n</font> 好消息是，09-04 13:51:20-09-04 13:51:21<font color=blue>Good news is,</font><br>161/358 314.76-317.1 <font color=red>de</font> 这样的系统在四多年前就已经出现了。09-04 13:51:21-09-04 13:51:48<font color=blue>Such a system has already been in existence for four years.</font><br>162/358 317.49-322.37 <font color=red>n</font> 如今全球睡眠呼吸领域的头部品牌 remed 就起步于这样发明。09-04 13:51:22-09-04 13:51:26<font color=blue>Remed, a leading brand in the global sleep apnea market, started with this invention.</font><br>163/358 322.73-323.27 <font color=red>aaa</font> 一九八零年，09-04 13:51:23-09-04 13:51:24<font color=blue>1980,</font><br>164/358 323.63-327.47 <font color=red>n</font> 西理大学的呼吸科研究员克林萨利文遇到了一个棘手的病人，09-04 13:51:23-09-04 13:51:28<font color=blue>A respiratory researcher at Trinity College, Dr. Clearsaw, encountered a particularly challenging patient.</font><br>165/358 327.81-329.28 <font color=red>jd</font> 作为重度 o s u 患者，09-04 13:51:24-09-04 13:51:25<font color=blue>As a heavy osu player,</font><br>166/358 329.46-331.32 <font color=red>hp</font> 每晚都在反复窒息中挣扎。09-04 13:51:25-09-04 13:51:29<font color=blue>Struggling in a constant state of suffocation every night.</font><br>167/358 331.77-332.97 <font color=red>aaa</font> 按当时的标准疗法，09-04 13:51:25-09-04 13:51:27<font color=blue>According to the standard treatment at that time,</font><br>168/358 333.15-334.83 <font color=red>jd</font> 他需要做气管切开手术，09-04 13:51:26-09-04 13:51:27<font color=blue>He needs to undergo a tracheotomy.</font><br>169/358 335.13-336.09 <font color=red>n</font> 在脖子上开个洞，09-04 13:51:27-09-04 13:51:28<font color=blue>Make a hole in your neck,</font><br>170/358 336.47-338.27 <font color=red>aaa</font> 绕过会塌陷的上气道呼吸。09-04 13:51:28-09-04 13:51:29<font color=blue>Bypass the collapsed upper airway to breathe.</font><br>171/358 338.77-340.21 <font color=red>jd</font> 但这位患者说什么也不干，09-04 13:51:28-09-04 13:51:30<font color=blue>But this patient refused to cooperate.</font><br>172/358 340.87-342.669 <font color=red>n</font> 萨丽雯当时正在研究睡眠，09-04 13:51:29-09-04 13:51:31<font color=blue>Sally was studying sleep at the time.</font><br>173/358 342.85-344.41 <font color=red>n</font> 对于呼吸和唱气道的影响，09-04 13:51:30-09-04 13:51:32<font color=blue>Regarding the effects on breathing and vocal cords,</font><br>174/358 344.53-348.05 <font color=red>hp</font> 他隐约觉得可以用空气把会塌陷的气道给撑住。09-04 13:51:30-09-04 13:51:35<font color=blue>He vaguely felt that he could use air to prop up the collapsed airway.</font><br>175/358 348.55-350.71 <font color=red>aaa</font> 问题是医院觉得这个想法太异想天开，09-04 13:51:31-09-04 13:51:33<font color=blue>The problem is that the hospital thinks this idea is too far-fetched.</font><br>176/358 350.83-351.73 <font color=red>jd</font> 完全不给他资援。09-04 13:51:32-09-04 13:51:34<font color=blue>Completely deny him funding.</font><br>177/358 352.15-353.35 <font color=red>n</font> 在经过患者的同意后，09-04 13:51:32-09-04 13:51:35<font color=blue>After obtaining the patient's consent,</font><br>178/358 353.53-355.99 <font color=red>n</font> 萨利文松实验室拆了一台鼓风机的电机，09-04 13:51:33-09-04 13:51:35<font color=blue>Sullivan's lab disassembled a fan motor.</font><br>179/358 356.17-356.65 <font color=red>aaa</font> 用来吹气，09-04 13:51:34-09-04 13:51:35<font color=blue>Used for blowing air,</font><br>180/358 357.05-360.92 <font color=red>jd</font> 又在医院里用硅胶管和粘合剂手工做了一个简易的比照，09-04 13:51:35-09-04 13:51:37<font color=blue>I also made a simple comparison using silicone tubes and adhesive in the hospital.</font><br>181/358 361.44-363.24 <font color=red>n</font> 把碗子直接贴在病人的鼻子上。09-04 13:51:35-09-04 13:51:37<font color=blue>Place the bowl directly against the patient's nose.</font><br>182/358 363.6-365.36 <font color=red>hp</font> 那天晚上这个在此之前，09-04 13:51:36-09-04 13:51:39<font color=blue>That night, before this.</font><br>183/358 365.6-367.64 <font color=red>aaa</font> 几乎没怎么睡过一个完整觉的病人，09-04 13:51:37-09-04 13:51:39<font color=blue>A patient who hasn't slept properly for a long time,</font><br>184/358 368.07-370.41 <font color=red>n</font> 安安稳稳的连续睡了大概七个小时以上。09-04 13:51:37-09-04 13:51:40<font color=blue>An is sleeping soundly and has been asleep for more than seven hours.</font><br>185/358 370.81-371.11 <font color=red>n</font> 第二年，09-04 13:51:38-09-04 13:51:40<font color=blue>In the second year,</font><br>186/358 371.35-373.51 <font color=red>jd</font> 萨利文在纽约刀上发表了这个论文，09-04 13:51:39-09-04 13:51:40<font color=blue>Sullivan published this paper on the New York knife.</font><br>187/358 373.84-378.28 <font color=red>hp</font> 报告了五名重度 o s a 患者在皮腔持续增压通气后症状缓解，09-04 13:51:40-09-04 13:51:46<font color=blue>Reported that five patients with severe OSA experienced symptom relief after intermittent positive airway pressure (IPAP) therapy.</font><br>188/358 378.61-381.34 <font color=red>aaa</font> 但这个发明在很长一段时间里都没能走出实验室。09-04 13:51:40-09-04 13:51:43<font color=blue>However, this invention was not able to leave the laboratory for a long time.</font><br>189/358 381.85-385.99 <font color=red>n</font> 早期的面罩是用每个患者鼻子的石膏模具翻制的玻璃纤维壳，09-04 13:51:41-09-04 13:51:46<font color=blue>The early masks were made of fiberglass shells, which were cast from plaster molds taken for each patient's nose.</font><br>190/358 386.58-388.439 <font color=red>jd</font> 每晚都要用硅胶胶水粘在脸上，09-04 13:51:42-09-04 13:51:44<font color=blue>Every night, I have to stick silicone glue on my face.</font><br>191/358 388.74-389.82 <font color=red>n</font> 早上再撕下来清洗，09-04 13:51:42-09-04 13:51:45<font color=blue>Wash it off again in the morning.</font><br>192/358 390.12-391.32 <font color=red>aaa</font> 这套操作非常麻烦，09-04 13:51:43-09-04 13:51:45<font color=blue>This operation is very complicated.</font><br>193/358 391.66-393.61 <font color=red>jd</font> 而且气流发生器用的还是水疗。09-04 13:51:46-09-04 13:51:48<font color=blue>In addition, the air flow generator also uses hydrotherapy.</font><br>194/358 393.91-396.46 <font color=red>aaa</font> 浴缸的涡流鼓风机将近七公斤，09-04 13:51:46-09-04 13:51:48<font color=blue>The whirlpool pump in the bathtub weighs almost seven kilograms.</font><br>195/358 396.7-397.48 <font color=red>n</font> 噪音大的离谱。09-04 13:51:48-09-04 13:51:49<font color=blue>The noise is outrageous.</font><br>196/358 397.91-400.19 <font color=red>hp</font> 新兴大学甚至拒绝为他的发明身体专利，09-04 13:51:48-09-04 13:51:53<font color=blue>Some emerging universities even refused to grant him a patent for his invention.</font><br>197/358 400.37-401.39 <font color=red>de</font> 觉得这东西太古怪，09-04 13:51:49-09-04 13:52:22<font color=blue>I think this thing is too weird.</font><br>198/358 401.76-404.13 <font color=red>de</font> 亚利文只好自己掏腰包成立一家公司，09-04 13:51:50-09-04 13:52:24<font color=blue>Alvin had to start his own company,</font><br>199/358 404.49-405.99 <font color=red>n</font> 买下了早期的技术专利。09-04 13:51:51-09-04 13:51:52<font color=blue>Acquired early-stage technology patents.</font><br>200/358 406.61-407.81 <font color=red>jd</font> 直到一九八六年，09-04 13:51:51-09-04 13:51:53<font color=blue>Until 1986,</font><br>201/358 407.99-411.17 <font color=red>bg</font> 萨利文遇到了巴克斯特医学研究中心的彼得法雷尔，09-04 13:51:52-09-04 13:52:48<font color=blue>Sullivan met Peter Farrell, a researcher at the Baxter Medical Research Center.</font><br>202/358 411.59-412.73 <font color=red>xss</font> 法亮看中了这项技术，09-04 13:51:53-09-04 13:53:32<font color=blue>Law saw the potential of this technology,</font><br>203/358 412.91-414.53 <font color=red>aaa</font> 随即推动他走向产品化，09-04 13:51:54-09-04 13:51:55<font color=blue>Then it drove him towards productization.</font><br>204/358 414.77-420.35 <font color=red>n</font> 并在第二年带领团队研发出了第一台可商用化的持续气道震压通气原型机。09-04 13:51:55-09-04 13:51:59<font color=blue>And in the second year, he led his team to develop the first commercially viable continuous airway pressure ventilation prototype.</font><br>205/358 420.83-422.809 <font color=red>n</font> 也就是我们今天常说的睡眠呼吸机。09-04 13:56:57-09-04 13:56:59<font color=blue>That is what we often call a sleep apnea machine.</font><br>206/358 423.26-423.92 <font color=red>n</font> 一九八九年，09-04 13:51:56-09-04 13:51:58<font color=blue>1989,</font><br>207/358 424.16-425.66 <font color=red>jd</font> 法利奥在悉尼创立一家公司，09-04 13:51:57-09-04 13:51:59<font color=blue>Faliyo founded a company in Sydney.</font><br>208/358 426.02-428.96 <font color=red>hp</font> 名字来自 respiratory medicine 的缩写 remed.09-04 13:51:58-09-04 13:52:02<font color=blue>The name comes from the abbreviation of respiratory medicine, remed.</font><br>209/358 429.32-430.1 <font color=red>aaa</font> 也就是瑞斯迈，09-04 13:51:59-09-04 13:52:00<font color=blue>That's Riesmeyer,</font><br>210/358 430.42-432.16 <font color=red>n</font> 为的就是把这个方案推向全世界。09-04 13:51:59-09-04 13:52:01<font color=blue>The goal is to promote this plan worldwide.</font><br>211/358 432.7-432.88 <font color=red>jd</font> 如今，09-04 13:52:00-09-04 13:52:01<font color=blue>Nowadays,</font><br>212/358 433.06-435.16 <font color=red>n</font> rem 的产品线已经涵盖自动震压、09-04 13:52:01-09-04 13:52:03<font color=blue>Rem's product line has already covered automatic pressure,</font><br>213/358 435.4-436.06 <font color=red>aaa</font> 双水平震压、09-04 13:52:02-09-04 13:52:03<font color=blue>Double-level seismic,</font><br>214/358 436.36-437.38 <font color=red>jd</font> 自适应伺浮通气、09-04 13:52:02-09-04 13:52:03<font color=blue>Adaptive ventilation,</font><br>215/358 437.77-438.79 <font color=red>n</font> 有创无创呼吸机、09-04 13:52:03-09-04 13:52:05<font color=blue>Ventilators, both invasive and non-invasive</font><br>216/358 438.85-439.33 <font color=red>hp</font> 多个种类。09-04 13:52:04-09-04 13:52:06<font color=blue>Multiple types.</font><br>217/358 439.65-444.15 <font color=red>n</font> 光面罩就比整视比照式全脸是好几个大类和十几个型号。09-04 13:52:04-09-04 13:52:10<font color=blue>Compared to the full-face helmet, there are several major categories and more than a dozen models of open face helmets.</font><br>218/358 444.58-445.0 <font color=red>jd</font> 不但如此，09-04 13:52:05-09-04 13:52:06<font color=blue>In addition,</font><br>219/358 445.3-450.94 <font color=red>aaa</font> rema 还自己设立了睡眠研究机构和全球多个大学以及医疗中心合作发表临床研究，09-04 13:52:06-09-04 13:52:13<font color=blue>Remo also established its own sleep research institute and collaborated with multiple universities and medical centers worldwide to publish clinical studies.</font><br>220/358 451.24-453.16 <font color=red>n</font> 累计专利超过一万零六百项，09-04 13:52:06-09-04 13:52:10<font color=blue>Accumulated over 1,060 patents.</font><br>221/358 453.59-454.97 <font color=red>jd</font> 还参与了无创呼吸机、09-04 13:52:07-09-04 13:52:10<font color=blue>Also participated in the development of non-invasive ventilators,</font><br>222/358 455.27-455.87 <font color=red>hp</font> 正压通气、09-04 13:52:08-09-04 13:52:10<font color=blue>Positive pressure ventilation,</font><br>223/358 455.99-456.35 <font color=red>jd</font> 呼吸机、09-04 13:52:11-09-04 13:52:12<font color=blue>Ventilator</font><br>224/358 456.59-457.07 <font color=red>n</font> 呼吸面罩、09-04 13:52:11-09-04 13:52:12<font color=blue>Breathing mask,</font><br>225/358 457.43-459.83 <font color=red>hp</font> 呼吸管路等中国行业标准的讨论和制定。09-04 13:52:12-09-04 13:52:16<font color=blue>Discussion and formulation of Chinese industry standards for respiratory equipment, etc.</font><br>226/358 460.35-460.71 <font color=red>jd</font> 事实上，09-04 13:52:13-09-04 13:52:14<font color=blue>In fact,</font><br>227/358 461.07-463.89 <font color=red>n</font> 家用呼吸机的核心原理直到今天也没有什么变化。09-04 13:52:14-09-04 13:52:17<font color=blue>The core principle of home ventilators has not changed much to this day.</font><br>228/358 464.07-467.55 <font color=red>aaa</font> 它本质上呢就是在往上气道送一股持续的正压气流，09-04 13:52:15-09-04 13:52:20<font color=blue>It is essentially delivering a continuous stream of positive pressure airflow to the upper airway.</font><br>229/358 467.91-469.38 <font color=red>jd</font> 像一个空气支架一样，09-04 13:52:15-09-04 13:52:17<font color=blue>Like an air support,</font><br>230/358 469.5-473.17 <font color=red>n</font> 从气道内部向外支撑软组织抵消吸气时的负压，09-04 13:52:16-09-04 13:52:20<font color=blue>To support soft tissues from the inside out, counteracting negative pressure during inhalation.</font><br>231/358 473.41-474.37 <font color=red>hp</font> 不让气到塌陷。09-04 13:52:17-09-04 13:52:20<font color=blue>Don't let them get to you.</font><br>232/358 474.75-476.79 <font color=red>jd</font> 但现实里的问题要比原理要复杂得多啊，09-04 13:52:18-09-04 13:52:20<font color=blue>But the actual problems are much more complex than the principles.</font><br>233/358 477.24-478.56 <font color=red>n</font> 每个人的气道结构不一样，09-04 13:52:18-09-04 13:52:20<font color=blue>Everyone has different airway structures.</font><br>234/358 478.74-479.94 <font color=red>jd</font> 需要的压力也不一样。09-04 13:52:21-09-04 13:52:22<font color=blue>The required pressure is also different.</font><br>235/358 480.37-482.35 <font color=red>n</font> 同一个人晚上会有不同的睡眠阶段，09-04 13:52:21-09-04 13:52:24<font color=blue>The same person will have different sleep stages at night.</font><br>236/358 482.53-484.87 <font color=red>aaa</font> 不同的睡觉姿势需要的压力也在变，09-04 13:52:22-09-04 13:52:26<font color=blue>The amount of pressure required for different sleeping positions also varies.</font><br>237/358 485.3-485.87 <font color=red>n</font> 压力给少了，09-04 13:52:23-09-04 13:52:24<font color=blue>Less pressure,</font><br>238/358 485.99-487.49 <font color=red>hp</font> 气道还是会塌陷给多了。09-04 13:52:23-09-04 13:52:26<font color=blue>The airway can collapse too much.</font><br>239/358 487.61-488.75 <font color=red>jd</font> 人又会觉得呼气困难，09-04 13:52:24-09-04 13:52:25<font color=blue>People will feel difficulty in breathing,</font><br>240/358 489.09-489.57 <font color=red>de</font> 根本睡不着，09-04 13:52:25-09-04 13:52:59<font color=blue>I can't sleep at all.</font><br>241/358 490.09-494.47 <font color=red>de</font> 再加上持续往鼻子里灌风容易口干面罩漏气会影响体验，09-04 13:52:25-09-04 13:53:31<font color=blue>In addition, continuously blowing air into the nose can cause dry mouth and the mask leaking air will affect the experience.</font><br>242/358 494.71-497.83 <font color=red>n</font> 这些甚至成为了 o s a 患者放弃使用的主要原因。09-04 13:52:26-09-04 13:52:31<font color=blue>These have become a major reason for patients with OSA to abandon treatment.</font><br>243/358 498.23-500.75 <font color=red>n</font> 毕竟每晚戴着一个不舒服的面罩睡觉真的很难。09-04 13:52:27-09-04 13:52:31<font color=blue>After all, it's really hard to sleep with an uncomfortable mask every night.</font><br>244/358 501.41-503.57 <font color=red>jd</font> 所以改善 o s a 的真正难点，09-04 13:52:27-09-04 13:52:31<font color=blue>The real difficulty in improving o.s.a. is,</font><br>245/358 503.81-505.61 <font color=red>hp</font> 一直都不是怎么把气道撑开，09-04 13:52:28-09-04 13:52:32<font color=blue>It has never been about how to keep the airway open.</font><br>246/358 505.97-507.59 <font color=red>aaa</font> 是面对一个睡眠状态，09-04 13:52:29-09-04 13:52:31<font color=blue>Facing a sleep state,</font><br>247/358 507.77-508.85 <font color=red>jd</font> 整晚都在变化的人，09-04 13:52:32-09-04 13:52:33<font color=blue>The person who changes all night,</font><br>248/358 509.03-510.11 <font color=red>n</font> 给了他正确的压力，09-04 13:52:32-09-04 13:52:33<font color=blue>Gave him the right pressure,</font><br>249/358 510.29-511.25 <font color=red>aaa</font> 让他睡得更舒服，09-04 13:52:33-09-04 13:52:34<font color=blue>Make him sleep better,</font><br>250/358 511.61-512.45 <font color=red>n</font> 愿意长久坚持。09-04 13:52:34-09-04 13:52:34<font color=blue>Willing to persevere.</font><br>251/358 513.09-513.63 <font color=red>hp</font> 换句话来说，09-04 13:52:34-09-04 13:52:36<font color=blue>In other words,</font><br>252/358 513.99-516.21 <font color=red>jd</font> 很多人需要的不只是一台能够吹气的机器，09-04 13:52:35-09-04 13:52:39<font color=blue>What many people need is not just a machine that can blow,</font><br>253/358 516.39-518.97 <font color=red>n</font> 而是一套能够在你睡着后持续感知、09-04 13:52:35-09-04 13:52:37<font color=blue>and continuously perceive while you are asleep.</font><br>254/358 519.33-519.57 <font color=red>aaa</font> 判断、09-04 13:52:36-09-04 13:52:37<font color=blue>Assessment,</font><br>255/358 519.99-520.29 <font color=red>n</font> 响应。09-04 13:52:37-09-04 13:52:37<font color=blue>Response.</font><br>256/358 520.65-524.43 <font color=red>n</font> 每晚都在正确舒适稳定运行的睡眠呼吸管理系统。09-04 13:57:40-09-04 13:57:43<font color=blue>A sleep apnea management system that runs correctly, comfortably and reliably every night.</font><br>257/358 524.91-527.67 <font color=red>hp</font> 这呢也是 race man 长期以来一直努力的方向，09-04 13:52:40-09-04 13:52:43<font color=blue>This is also a long-term goal of race men.</font><br>258/358 527.97-531.75 <font color=red>aaa</font> 站在一个 o s c 患者的角度判断一套睡眠呼吸系统靠不靠谱，09-04 13:52:40-09-04 13:52:43<font color=blue>From the perspective of an OSCC patient, how reliable is a sleep apnea treatment?</font><br>259/358 531.99-532.89 <font color=red>n</font> 主要看几个问题。09-04 13:52:41-09-04 13:52:42<font color=blue>Focus on a few key questions.</font><br>260/358 533.21-533.39 <font color=red>n</font> 第一，09-04 13:52:42-09-04 13:52:42<font color=blue>First,</font><br>261/358 533.57-540.01 <font color=red>jd</font> 他是不是知道你需要帮助 resma 自动调压睡眠呼吸机会搭载一个叫做 auto set 的算法，09-04 13:52:42-09-04 13:52:46<font color=blue>Does he know that you need help? The Resma automatic pressure sleep apnea device is equipped with an algorithm called "auto set".</font><br>262/358 540.19-542.41 <font color=red>n</font> 这个算法会持续监测起到状态。09-04 13:52:43-09-04 13:52:45<font color=blue>This algorithm continuously monitors the status.</font><br>263/358 542.71-543.43 <font color=red>n</font> 通过气流受限、09-04 13:52:44-09-04 13:52:45<font color=blue>Through airflow restriction,</font><br>264/358 543.67-545.41 <font color=red>aaa</font> 打鼾和呼吸暂停三个参数，09-04 13:52:44-09-04 13:52:46<font color=blue>The three parameters of snoring, apnea and breathing cessation.</font><br>265/358 545.71-547.81 <font color=red>hp</font> 动态分析患者上呼吸道的状态，09-04 13:52:45-09-04 13:52:49<font color=blue>Analyze the patient's upper respiratory tract status.</font><br>266/358 547.99-550.869 <font color=red>n</font> 并根据阻塞的程度在允许的范围内输出压力。09-04 13:52:46-09-04 13:52:49<font color=blue>And output the pressure within an allowed range according to the degree of blockage.</font><br>267/358 551.2-552.88 <font color=red>n</font> 如果检测到气流开始变平，09-04 13:52:47-09-04 13:52:49<font color=blue>If the airflow starts to become flat,</font><br>268/358 553.179-554.44 <font color=red>jd</font> 说明气道正在变窄，09-04 13:52:47-09-04 13:52:48<font color=blue>Explain that the airway is narrowing.</font><br>269/358 554.8-556.18 <font color=red>aaa</font> 算法就小幅提升压力。09-04 13:52:48-09-04 13:52:50<font color=blue>The algorithm has a slight improvement in pressure.</font><br>270/358 556.53-557.31 <font color=red>bg</font> 如果出现了鼾声，09-04 13:52:49-09-04 13:53:14<font color=blue>If there is snoring,</font><br>271/358 557.61-559.71 <font color=red>jd</font> 说明软组织已在震动了压力，09-04 13:52:50-09-04 13:52:52<font color=blue>Explain that soft tissue has been subjected to pressure.</font><br>272/358 559.77-561.51 <font color=red>hp</font> 会根据鼾声的响度继续上调。09-04 13:52:51-09-04 13:52:55<font color=blue>The volume will be increased further based on the loudness of snoring.</font><br>273/358 561.95-563.15 <font color=red>n</font> 如果出现了呼吸暂停，09-04 13:52:51-09-04 13:52:53<font color=blue>If there is a breathing pause,</font><br>274/358 563.45-563.75 <font color=red>n</font> 算法，09-04 13:52:52-09-04 13:52:53<font color=blue>Algorithm,</font><br>275/358 563.99-565.85 <font color=red>aaa</font> 会在暂停结束的那一刻加压，09-04 13:52:53-09-04 13:52:54<font color=blue>The pressure will increase at the end of the pause.</font><br>276/358 566.09-567.59 <font color=red>jd</font> 同时把压力水平记录下来。09-04 13:52:53-09-04 13:52:55<font color=blue>Also, record the stress level.</font><br>277/358 567.81-568.77 <font color=red>n</font> 一旦呼吸稳定了，09-04 13:52:54-09-04 13:52:55<font color=blue>Once the breathing is stable,</font><br>278/358 568.89-569.97 <font color=red>n</font> 压力就会慢慢降回来，09-04 13:52:55-09-04 13:52:56<font color=blue>The pressure will gradually subside.</font><br>279/358 570.21-571.38 <font color=red>aaa</font> 不会一直维持在高位。09-04 13:52:55-09-04 13:52:57<font color=blue>It won't stay at a high level forever.</font><br>280/358 571.75-573.07 <font color=red>jd</font> 整个过程的目标只有一个，09-04 13:52:57-09-04 13:52:58<font color=blue>The only goal of the entire process is one.</font><br>281/358 573.31-576.55 <font color=red>n</font> 用最小压力来保持病人的上气道持续开放。09-04 13:52:57-09-04 13:53:00<font color=blue>Maintain the patient's airway with minimal pressure.</font><br>282/358 576.94-577.18 <font color=red>n</font> 要知道，09-04 13:52:58-09-04 13:52:59<font color=blue>To be honest,</font><br>283/358 577.36-579.16 <font color=red>aaa</font> 很多家用呼吸机是固定压力的，09-04 13:52:59-09-04 13:53:00<font color=blue>Many home ventilators are fixed pressure,</font><br>284/358 579.44-582.02 <font color=red>jd</font> 这个压力通常是按照最严重的时刻来定的。09-04 13:52:59-09-04 13:53:01<font color=blue>This pressure is usually determined according to the most severe time.</font><br>285/358 582.43-584.89 <font color=red>hp</font> 但患者不是每时每刻都需要那么大的劲儿，09-04 13:53:00-09-04 13:53:05<font color=blue>But patients don't always need so much strength.</font><br>286/358 585.13-587.29 <font color=red>de</font> 很多时候反而会因为压力过大而影响入睡。09-04 13:53:01-09-04 13:53:31<font color=blue>Often, it can be due to excessive pressure that affects sleep.</font><br>287/358 587.84-590.42 <font color=red>n</font> auto set 就相当于一个全程值班的呼吸管家，09-04 13:53:01-09-04 13:53:05<font color=blue>auto set is equivalent to a full-time respiratory care provider.</font><br>288/358 590.6-591.92 <font color=red>n</font> 只在你需要的时候吹气。09-04 13:53:02-09-04 13:53:05<font color=blue>Blow only when you need to.</font><br>289/358 592.34-592.52 <font color=red>aaa</font> 第二，09-04 13:53:03-09-04 13:53:03<font color=blue>Second,</font><br>290/358 592.76-595.22 <font color=red>jd</font> 它能不能让你每天晚上都能坚持用下去。09-04 13:53:04-09-04 13:53:07<font color=blue>Can it help you to stick to it every night?</font><br>291/358 595.54-597.07 <font color=red>aaa</font> 很多人第一次带呼吸机会带不住，09-04 13:53:06-09-04 13:53:08<font color=blue>Many people find it difficult to hold their breath for the first time.</font><br>292/358 597.43-598.45 <font color=red>hp</font> 大多是觉得风太大，09-04 13:53:06-09-04 13:53:09<font color=blue>Most people think it's too windy.</font><br>293/358 598.51-598.99 <font color=red>n</font> 吹得难受。09-04 13:53:07-09-04 13:53:09<font color=blue>It's hard to breathe.</font><br>294/358 599.33-603.05 <font color=red>n</font> 但 auto rap 的功能会在开机以后设置一个很低的起始压力。09-04 13:53:08-09-04 13:53:12<font color=blue>However, the auto-rap function will set a very low starting pressure after startup.</font><br>295/358 603.37-604.84 <font color=red>jd</font> 等他检测到你真的睡着了，09-04 13:53:08-09-04 13:53:10<font color=blue>Wait until he detects that you are really asleep,</font><br>296/358 604.9-606.7 <font color=red>aaa</font> 才慢慢把压力升到合适的水平。09-04 13:53:09-09-04 13:53:10<font color=blue>Gradually increase the pressure to a suitable level.</font><br>297/358 607.01-609.26 <font color=red>n</font> 不过一开机就一大股风怼到你脸上，09-04 13:53:09-09-04 13:53:14<font color=blue>But as soon as you turn it on, a gust of wind will blow directly into your face.</font><br>298/358 609.62-610.64 <font color=red>hp</font> 然后是呼际体验。09-04 13:53:10-09-04 13:53:13<font color=blue>Then comes the experience of interaction.</font><br>299/358 610.92-612.06 <font color=red>jd</font> 正常呼吸时吸气，09-04 13:53:11-09-04 13:53:12<font color=blue>Normal breathing, inhale.</font><br>300/358 612.24-612.6 <font color=red>aaa</font> 更用力，09-04 13:53:12-09-04 13:53:12<font color=blue>More effort,</font><br>301/358 612.96-613.14 <font color=red>n</font> 呼气，09-04 13:53:13-09-04 13:53:14<font color=blue>Exhale,</font><br>302/358 613.32-613.8 <font color=red>jd</font> 向对放松。09-04 13:53:13-09-04 13:53:14<font color=blue>Relax.</font><br>303/358 614.25-615.15 <font color=red>aaa</font> 如果在呼气时，09-04 13:53:14-09-04 13:53:15<font color=blue>When exhaling,</font><br>304/358 615.45-616.53 <font color=red>hp</font> 面罩里还有额外的压力，09-04 13:53:15-09-04 13:53:17<font color=blue>There is additional pressure inside the mask.</font><br>305/358 616.71-617.55 <font color=red>n</font> 就会感觉到不舒服。09-04 13:53:15-09-04 13:53:17<font color=blue>You will feel uncomfortable.</font><br>306/358 618.04-621.82 <font color=red>n</font> resm 的 e p r 功能会在呼气阶段适当降低压力，09-04 13:53:16-09-04 13:53:19<font color=blue>The e p r function of resm will appropriately reduce pressure during the exhalation phase.</font><br>307/358 622.0-623.26 <font color=red>jd</font> 在继续支撑气道的同时，09-04 13:53:17-09-04 13:53:18<font color=blue>While continuing to support the airway,</font><br>308/358 623.5-625.24 <font color=red>bg</font> 让呼气变得更加轻松自然。09-04 13:53:17-09-04 13:53:50<font color=blue>Make breathing easier and more natural.</font><br>309/358 625.78-626.62 <font color=red>aaa</font> 有的人带呼吸机，09-04 13:53:18-09-04 13:53:19<font color=blue>Some people are carrying respirators.</font><br>310/358 626.74-627.52 <font color=red>n</font> 还会觉得鼻子干，09-04 13:53:19-09-04 13:53:20<font color=blue>Still feel dry nose,</font><br>311/358 627.88-628.84 <font color=red>hp</font> 持续往鼻子里面灌，09-04 13:53:19-09-04 13:53:22<font color=blue>Keep pouring into the nose,</font><br>312/358 628.96-629.92 <font color=red>jd</font> 干冷的空气谁都受不了。09-04 13:53:20-09-04 13:53:21<font color=blue>The cold air is unbearable.</font><br>313/358 630.1-632.92 <font color=red>n</font> 但 re pad 的很多呼吸机都内置了加温加湿器，09-04 13:53:21-09-04 13:53:25<font color=blue>However, many Respironics ventilators have built-in heating and humidification devices.</font><br>314/358 633.26-634.67 <font color=red>aaa</font> 如果搭配它的恒温管路，09-04 13:53:21-09-04 13:53:23<font color=blue>If combined with its temperature control system,</font><br>315/358 634.79-636.05 <font color=red>n</font> 还能够自动调节温湿度，09-04 13:53:22-09-04 13:53:25<font color=blue>It can also automatically adjust temperature and humidity.</font><br>316/358 636.17-637.07 <font color=red>jd</font> 不用你手动调节。09-04 13:53:23-09-04 13:53:24<font color=blue>No manual adjustment required.</font><br>317/358 637.41-639.33 <font color=red>hp</font> 身边呢很多家用呼吸机的噪音都不小，09-04 13:53:23-09-04 13:53:27<font color=blue>The noise of many household ventilators is quite loud.</font><br>318/358 639.63-640.77 <font color=red>aaa</font> 不光用的人睡不好，09-04 13:53:24-09-04 13:53:27<font color=blue>Not only do people use it, but they also can't sleep well.</font><br>319/358 640.95-641.97 <font color=red>jd</font> 枕边的人也跟着遭殃。09-04 13:53:25-09-04 13:53:27<font color=blue>The person beside me also suffers.</font><br>320/358 642.3-645.96 <font color=red>n</font> 但是 rem 的大部分产品噪音甚至可以控制在二十五分贝左右，09-04 13:53:26-09-04 13:53:30<font color=blue>However, the noise of most products from rem can even be controlled at around 25 decibels.</font><br>321/358 646.31-648.35 <font color=red>n</font> 尽量减少对自己和这边人的打扰。09-04 13:53:27-09-04 13:53:29<font color=blue>Minimize disturbance to yourself and others.</font><br>322/358 648.79-648.97 <font color=red>aaa</font> 第三，09-04 13:53:27-09-04 13:53:28<font color=blue>Third,</font><br>323/358 649.27-652.33 <font color=red>jd</font> 它能不能让整个过程变得可追终可调整。09-04 13:53:28-09-04 13:53:30<font color=blue>Can it make the entire process traceable and adjustable?</font><br>324/358 652.94-655.22 <font color=red>hp</font> o s a 是一个需要长期管理的疾病，09-04 13:53:29-09-04 13:53:33<font color=blue>o s a is a chronic disease that requires long-term management.</font><br>325/358 655.75-658.03 <font color=red>aaa</font> resm 的呼吸机会记录使用时长、09-04 13:53:29-09-04 13:53:31<font color=blue>resm's record of breathing opportunities,</font><br>326/358 658.57-660.79 <font color=red>n</font> 残余呼吸事件和漏气量等关键数据，09-04 13:53:30-09-04 13:53:32<font color=blue>Residual breathing events and leakage volume,</font><br>327/358 660.91-661.93 <font color=red>jd</font> 并同步到手机应用，09-04 13:53:31-09-04 13:53:32<font color=blue>and also synchronize to the mobile app,</font><br>328/358 662.21-663.71 <font color=red>n</font> 让你查看每晚的睡眠数据，09-04 13:53:31-09-04 13:53:33<font color=blue>Let you view your sleep data every night,</font><br>329/358 663.95-664.73 <font color=red>de</font> 方便后续管理。09-04 13:53:33-09-04 13:53:54<font color=blue>For easier subsequent management.</font><br>330/358 665.11-666.01 <font color=red>n</font> 而所有的这一切，09-04 13:58:35-09-04 13:58:36<font color=blue>All of this,</font><br>331/358 666.31-666.73 <font color=red>aaa</font> 归结起来，09-04 13:53:34-09-04 13:53:35<font color=blue>In summary,</font><br>332/358 666.79-667.27 <font color=red>n</font> 就一句话，09-04 13:53:35-09-04 13:53:36<font color=blue>In one sentence,</font><br>333/358 667.85-669.77 <font color=red>jd</font> 让你在夜晚睡眠的这几个小时里，09-04 13:53:36-09-04 13:53:38<font color=blue>Here are a few things that can help you get a good night's sleep:</font><br>334/358 670.01-671.15 <font color=red>xss</font> 依然能够安稳的呼吸。09-04 13:53:36-09-04 13:55:08<font color=blue>Still able to breathe smoothly.</font><br>335/358 671.61-672.15 <font color=red>hp</font> 时至今日，09-04 13:53:37-09-04 13:53:39<font color=blue>Today,</font><br>336/358 672.33-673.89 <font color=red>n</font> 我们对于睡眠的了解依然有限。09-04 13:53:38-09-04 13:53:39<font color=blue>Our understanding of sleep is still limited.</font><br>337/358 674.34-675.18 <font color=red>aaa</font> 但我们可以确定的是，09-04 13:53:38-09-04 13:53:40<font color=blue>But we can definitely say that,</font><br>338/358 675.36-677.64 <font color=red>n</font> 睡眠从来不是一段被浪费掉的时间。09-04 13:53:39-09-04 13:53:40<font color=blue>Sleep is never a wasted time.</font><br>339/358 678.14-679.28 <font color=red>jd</font> 在一个完整的睡眠里，09-04 13:53:40-09-04 13:53:41<font color=blue>In a complete sleep,</font><br>340/358 679.52-680.66 <font color=red>hp</font> 身体在调节代谢、09-04 13:53:40-09-04 13:53:43<font color=blue>Body regulates metabolism,</font><br>341/358 681.02-681.68 <font color=red>n</font> 免疫和激素，09-04 13:53:41-09-04 13:53:43<font color=blue>Immunity and hormones,</font><br>342/358 682.13-683.81 <font color=red>aaa</font> 呼吸和心血管系统也在持续运转。09-04 13:53:42-09-04 13:53:45<font color=blue>The respiratory and cardiovascular systems are still functioning.</font><br>343/358 684.13-685.99 <font color=red>n</font> 白天呢我们愿意管理饮食运动，09-04 13:53:44-09-04 13:53:47<font color=blue>During the day, we are willing to manage diet and exercise.</font><br>344/358 686.17-687.31 <font color=red>jd</font> 关注各种身理指标。09-04 13:53:45-09-04 13:53:46<font color=blue>Monitor various physical indicators.</font><br>345/358 687.55-689.83 <font color=red>n</font> 但睡着后的这段时间却常常忽略掉。09-04 13:53:45-09-04 13:53:49<font color=blue>However, this period of time after falling asleep is often overlooked.</font><br>346/358 690.07-691.09 <font color=red>hp</font> 对 o s a 患者来说，09-04 13:53:46-09-04 13:53:48<font color=blue>For OSAS patients,</font><br>347/358 691.27-692.05 <font color=red>aaa</font> 问题尤为明显。09-04 13:53:47-09-04 13:53:48<font color=blue>The problem is particularly obvious.</font><br>348/358 692.42-694.67 <font color=red>jd</font> 他的呼吸可能在夜晚经历过数次中断，09-04 13:53:47-09-04 13:53:49<font color=blue>His breathing may have been interrupted several times at night.</font><br>349/358 694.91-695.99 <font color=red>n</font> 但自己却毫不知情。09-04 13:53:48-09-04 13:53:49<font color=blue>But he was completely unaware.</font><br>350/358 696.31-701.86 <font color=red>aaa</font> 这也是为什么在四十多年前就已经被证明的正压通气技术到今天仍再不断进步。09-04 13:53:49-09-04 13:53:53<font color=blue>This is also why the positive pressure ventilation technique, which has been proven for over 40 years, continues to be constantly improved today.</font><br>351/358 702.1-703.9 <font color=red>hp</font> 因为它需要在一个个真实的人身上，09-04 13:53:49-09-04 13:53:52<font color=blue>Because it requires a real person,</font><br>352/358 704.08-706.0 <font color=red>n</font> 而且得保证每晚都可以更准确、09-04 13:53:50-09-04 13:53:53<font color=blue>And ensure that it can be more accurate every night,</font><br>353/358 706.12-706.48 <font color=red>jd</font> 更舒适、09-04 13:53:51-09-04 13:53:51<font color=blue>More comfortable,</font><br>354/358 706.66-707.32 <font color=red>n</font> 更稳定的运行。09-04 13:53:51-09-04 13:53:53<font color=blue>More stable operation.</font><br>355/358 707.72-710.3 <font color=red>bg</font> 毕竟呢睡眠占据了人生的三分之一，09-04 13:53:52-09-04 13:54:43<font color=blue>After all, sleep occupies one-third of a person's life.</font><br>356/358 710.65-712.21 <font color=red>jd</font> 这样一段漫长重要，09-04 13:53:53-09-04 13:53:54<font color=blue>This is a long and important passage.</font><br>357/358 712.33-714.25 <font color=red>hp</font> 又无法有意识主动接管的时间，09-04 13:53:53-09-04 13:53:57<font color=blue>Time that cannot be consciously and actively controlled.</font><br>358/358 714.68-716.12 <font color=red>aaa</font> 值得被更认真的对待。09-04 13:53:54-09-04 13:53:55<font color=blue>Deserves to be taken seriously.</font><br>